Mastifort DC

Mastifort DC

• For simultaneous drying-off and treatment of mastitis of bacterial etiology in cows during the dry period
• Combination of ampicillin and cloxacillin
• Prolonged antimicrobial action within 48 days after administration
• Single injection

Pharmaceutical group: For the treatment of mastitis

Active ingredients: ampicillin trihydrate, cloxacillin benzathine

Release form: Plastic syringes of 10 cm3 for intracisternal administration

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Description

Compound

Pharmacological properties

Indications for use

Dosage and method of application

Contraindications

Restrictions

Veterinary drug for the treatment of mastitis during the dry period

• For simultaneous drying-off and treatment of mastitis of bacterial etiology in cows during the dry period
• Combination of ampicillin and cloxacillin
• Prolonged antimicrobial action within 48 days after administration
• Single injection

One dose of the drug (10 cm3) contains active ingredients: ampicillin trihydrate 250 mg, cloxacillin benzathine 500 mg
Mastifort DC is a combination of sparingly soluble salts of semi-synthetic penicillins - ampicillin and cloxacillin, which has bactericidal activity against mastitis pathogens isolated from the udder secretion of cows during the dry period Streptococcus spp., Staphylococcus spp., Clostridium spp., Corynebacterium pyogenes, Esherichia coli, including those resistant to penicillin, whose resistance is due to β-lactamase.

The base and sparingly soluble salts of antibiotics provide a prolonged antimicrobial effect of the drug.
Mastifort DC is used for immediate drying-off and treatment of mastitis of bacterial etiology in cows during the dry period.
Mastifort DC is administered to cows after the last milking before transfer to the dry period, but no later than 42 days before the expected calving, once, intracisternally, 10 cm3 (contents of 1 syringe) in each quarter of the udder.

Before the introduction of the drug, the udder milk is milked out; the teat is treated with a disinfectant solution.

The cannula of the syringe is placed in the teat canal and the contents are gently injected into a quarter of the udder.

The syringe is taken out and the teat is pressed with fingers for 1-2 minutes. A light massage of the teat is carried out for better distribution of the drug.

In case of low ambient temperature, before use, the drug must be heated to a temperature of 37-39 °C.
The drug is contraindicated in animals with hypersensitivity to one of the ingredients of the drug.

It should not be administered simultaneously with other antibacterial drugs.

It is forbidden to administer to cows during lactation and less than 42 days before the expected calving due to the long-term excretion of cloxacillin with milk. If the drug was erroneously administered to lactating cows, then milk should not be used for food within 46 days.
MEAT – 28 days after drug administration.
MILK – 7 days after calving.

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