Argoflu

Argoflu

• Without antibiotics
• Has anti-inflammatory and antimicrobial effect
• Helps reduce inflammation, pain and swelling
• Has a pronounced antiseptic and anti-inflammatory effect
• After intrauterine administration, it is quickly distributed over the entire surface of the endometrium
• Retains therapeutic concentrations for at least 24 hours

Pharmaceutical group: For KPC in the treatment of endometritis and metritis

Active ingredients: flunixin meglumine, colloidal silver

Release form: Plastic syringes of 30 g net weight

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Description

Compound

Pharmacological properties

Indications for use

Dosage and method of application

Contraindications

Restrictions

Suspension for intrauterine administration

A complex preparation for the treatment of endometritis in cows, as well as for prophylactic purposes after cesarean section, obstetric care, surgical separation of the placenta

• Without antibiotics
• Has anti-inflammatory and antimicrobial effect
• Helps reduce inflammation, pain and swelling
• Has a pronounced antiseptic and anti-inflammatory effect
• After intrauterine administration, it is quickly distributed over the entire surface of the endometrium
• Retains therapeutic concentrations for at least 24 hours
1 g of the drug contains active ingredients: flunixin meglumine 50 mg, silver (in the form of colloidal silver) 850 mcg
Flunixin meglumine, a non-steroidal anti-inflammatory agent of a fenamate group, has a pronounced anti-inflammatory, analgesic and antipyretic effect.

The mechanism of action of flunixin meglumine is based on the ability to suppress the production of cyclooxygenases (COX-1 and COX-2), thereby inhibiting the synthesis of prostaglandins E2, inflammatory mediators, under the influence of which the synthesis of inflammatory prostaglandins occurs, causing inflammation, swelling and pain.

Silver (presented as colloidal silver) has a wide spectrum of antimicrobial activity against gram-negative (Escherichia coli, Klebsiella spp., Salmonella spp., Proteus spp., Campylobacter spp., Pseudomonas aeruginosa, Bordetella spp., Pasteurella spp., Haemophilus spp., Fusobacterium necrophorum) and gram-positive bacteria (Streptococcus spp., Enterococcus faecalis, Staphylococcus spp., including those producing beta-lactamase, Clostridium spp.), and chlamydia. Some fungi are sensitive to silver (Candida spp., Aspergillus spp.).

The mechanism of the anti-inflammatory action of silver is based on the ability to precipitate proteins on the surface of the damaged mucosa with the formation of a protective film. This helps to reduce the sensitivity of mucous membranes and activates vasoconstriction, which leads to inhibition of inflammatory reactions.

The mechanism of the antimicrobial action of silver is due to the ability to bind to the DNA of bacteria, which prevents their reproduction on the mucous membranes.
Argoflu is used in cows:
- for the treatment of inflammatory processes of the uterus (clinical and subclinical endometritis),
- for prophylactic purposes after caesarean section, obstetric care, surgical separation of the placenta.
Before using the drug, it is necessary to sanitize the external genital organs and the root of the tail of the animal. If necessary, free the uterine cavity from inflammatory exudate.

Before use, the syringe is connected to a pipette, a disposable polyethylene glove is put on the hand for rectal fixation of the cervix, then the pipette is carefully inserted through the cervical canal into the uterine cavity and the contents of the syringe are injected.

The drug is administered intrauterine, using a disposable pipette and glove.
- in case of clinical endometritis at a dose of 30 g with an interval of 24 hours 3-5 times.
- in case of subclinical endometritis at a dose of 30 g once, if necessary, repeat in 24 hours.
- for prophylactic purposes (after surgical separation of the placenta, caesarean section, obstetrics) at a dose of 30 g once, if necessary, repeat in 24 hours.
The use of the drug in animals with uterine ruptures, with allergic reactions to the ingredients of the drug is contraindicated.

Do not use together with iodine-containing drugs, as they reduce the antimicrobial activity of the drug.
MILK, MEAT – 120 hours.

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