ПРЕПАРАТЫ ДЛЯ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ ЭНДОМЕТРИТОВ

Суспензия Ниокситил
Корова
Суспензия Ниокситил
Препарат применяют при лечении и профилактике эндометритов у коров. Препарат представляет собой густую, слегка расслаивающуюся жидкость, от темно-желтого до коричневого цвета, допускается наличие рыхлого осадка. Форма выпуска: пластмассовые флаконы по 100,0; 200,0; 500,0 и 1000,0 см3. Препарат предназначен для внутриматочного введения.
Срок годности: 2 года от даты изготовления при соблюдении условий хранения.
Условия хранения: Препарат хранят по списку Б в защищенном от света месте при температуре от +2°С до +25°С. Замораживание не допускается.

Входящие в состав препарата тилозина тартрат, окситетрациклина гидрохлорид и нитроксолин оказывают выраженное антимикробное действие на широкий спектр грамположительных и грамотрицательных микроорганизмов, а также на грибы, микоплазмы и хламидии. Пропранолола гидрохлорид тонизирует мускулатуру матки, тем самым способствует удалению патологического содержимого из ее полости и способствует процессу клинического выздоровления коров, больных эндометритом. 


Препарат вводят внутриматочно в дозе 10-15 см3/100 кг массы телы животного с помощью шприца Жане, с интервалом 48-72 ч до выздоровления. Перед использованием препарат необходимо подогреть до температуры от +36 до + 38˚С.
С профилактической целью суспензию «Ниокситил» вводят внутриматочно, однократно, после отделения последа в дозе 10 см3/100 кг массы тела животного.
При соблюдении дозировки препарат побочных явлений не вызывает.
В случае возникновения побочных явлений в виде аллергических реакций (крапивница, зуд кожи) рекомендуется применение препарата прекратить и назначить антигистаминные препараты и препараты кальция.
Убой животных на мясо и использование молока в пищу людям разрешено не ранее, чем через 20 суток после последнего применения препарата. В случае вынужденого убоя животных ранее указанного срока мясо используется на корм плотоядным животным. До истечения указанного срока молоко скармливают плотоядным животным после кипячения. 

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    7
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    Filesystem.php
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    Filesystem.php
         *
         * @param  string  $path
         * @return string
         */
        public function hash($path)
        {
            return md5_file($path);
        }
     
        /**
         * Write the contents of a file.
         *
         * @param  string  $path
         * @param  string  $contents
         * @param  bool  $lock
         * @return int
         */
        public function put($path, $contents, $lock = false)
        {
            return file_put_contents($path, $contents, $lock ? LOCK_EX : 0);
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        /**
         * Prepend to a file.
         *
         * @param  string  $path
         * @param  string  $data
         * @return int
         */
        public function prepend($path, $data)
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            if ($this->exists($path)) {
                return $this->put($path, $data.$this->get($path));
            }
     
            return $this->put($path, $data);
        }
     
        /**
         * Append to a file.
    Arguments
    1. "file_put_contents(): Only 0 of 200 bytes written, possibly out of free disk space"
      
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    Filesystem.php
         *
         * @param  string  $path
         * @return string
         */
        public function hash($path)
        {
            return md5_file($path);
        }
     
        /**
         * Write the contents of a file.
         *
         * @param  string  $path
         * @param  string  $contents
         * @param  bool  $lock
         * @return int
         */
        public function put($path, $contents, $lock = false)
        {
            return file_put_contents($path, $contents, $lock ? LOCK_EX : 0);
        }
     
        /**
         * Prepend to a file.
         *
         * @param  string  $path
         * @param  string  $data
         * @return int
         */
        public function prepend($path, $data)
        {
            if ($this->exists($path)) {
                return $this->put($path, $data.$this->get($path));
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            return $this->put($path, $data);
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        /**
         * Append to a file.
    Arguments
    1. "/var/www/belkarolin/data/www/belkarolin.com/storage/framework/sessions/TOSr8uvdBfhScuNl8PrPaHbyeWxbp40DN7u14S7y"
      
    2. "a:3:{s:6:"_token";s:40:"O0WBOqXQ93fmAiuw8Fv4YB2Co5ztTwupQdaRJ1Do";s:9:"_previous";a:1:{s:3:"url";s:42:"http://belkarolin.com/catalog/products/nio";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
      
    3. 2
      
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    src
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    Session
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    FileSessionHandler.php
        /**
         * {@inheritdoc}
         */
        public function read($sessionId)
        {
            if ($this->files->exists($path = $this->path.'/'.$sessionId)) {
                if (filemtime($path) >= Carbon::now()->subMinutes($this->minutes)->getTimestamp()) {
                    return $this->files->get($path, true);
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            return '';
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        /**
         * {@inheritdoc}
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        public function write($sessionId, $data)
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            $this->files->put($this->path.'/'.$sessionId, $data, true);
     
            return true;
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        /**
         * {@inheritdoc}
         */
        public function destroy($sessionId)
        {
            $this->files->delete($this->path.'/'.$sessionId);
     
            return true;
        }
     
        /**
         * {@inheritdoc}
         */
        public function gc($lifetime)
        {
            $files = Finder::create()
    Arguments
    1. "/var/www/belkarolin/data/www/belkarolin.com/storage/framework/sessions/TOSr8uvdBfhScuNl8PrPaHbyeWxbp40DN7u14S7y"
      
    2. "a:3:{s:6:"_token";s:40:"O0WBOqXQ93fmAiuw8Fv4YB2Co5ztTwupQdaRJ1Do";s:9:"_previous";a:1:{s:3:"url";s:42:"http://belkarolin.com/catalog/products/nio";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
      
    3. true
      
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    Session
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    Store.php
         *
         * @param  string  $data
         * @return string
         */
        protected function prepareForUnserialize($data)
        {
            return $data;
        }
     
        /**
         * Save the session data to storage.
         *
         * @return bool
         */
        public function save()
        {
            $this->ageFlashData();
     
            $this->handler->write($this->getId(), $this->prepareForStorage(
                serialize($this->attributes)
            ));
     
            $this->started = false;
        }
     
        /**
         * Prepare the serialized session data for storage.
         *
         * @param  string  $data
         * @return string
         */
        protected function prepareForStorage($data)
        {
            return $data;
        }
     
        /**
         * Age the flash data for the session.
         *
         * @return void
    Arguments
    1. "TOSr8uvdBfhScuNl8PrPaHbyeWxbp40DN7u14S7y"
      
    2. "a:3:{s:6:"_token";s:40:"O0WBOqXQ93fmAiuw8Fv4YB2Co5ztTwupQdaRJ1Do";s:9:"_previous";a:1:{s:3:"url";s:42:"http://belkarolin.com/catalog/products/nio";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
      
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    Session
    /
    Middleware
    /
    StartSession.php
            if ($this->sessionConfigured()) {
                $this->storeCurrentUrl($request, $session);
     
                $this->addCookieToResponse($response, $session);
            }
     
            return $response;
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        /**
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         *
         * @param  \Illuminate\Http\Request  $request
         * @param  \Symfony\Component\HttpFoundation\Response  $response
         * @return void
         */
        public function terminate($request, $response)
        {
            if ($this->sessionHandled && $this->sessionConfigured() && ! $this->usingCookieSessions()) {
                $this->manager->driver()->save();
            }
        }
     
        /**
         * Start the session for the given request.
         *
         * @param  \Illuminate\Http\Request  $request
         * @return \Illuminate\Contracts\Session\Session
         */
        protected function startSession(Request $request)
        {
            return tap($this->getSession($request), function ($session) use ($request) {
                $session->setRequestOnHandler($request);
     
                $session->start();
            });
        }
     
        /**
         * Get the session implementation from the manager.
    /
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    Kernel.php
         * @return void
         */
        protected function terminateMiddleware($request, $response)
        {
            $middlewares = $this->app->shouldSkipMiddleware() ? [] : array_merge(
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                $this->middleware
            );
     
            foreach ($middlewares as $middleware) {
                if (! is_string($middleware)) {
                    continue;
                }
     
                list($name) = $this->parseMiddleware($middleware);
     
                $instance = $this->app->make($name);
     
                if (method_exists($instance, 'terminate')) {
                    $instance->terminate($request, $response);
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            }
        }
     
        /**
         * Gather the route middleware for the given request.
         *
         * @param  \Illuminate\Http\Request  $request
         * @return array
         */
        protected function gatherRouteMiddleware($request)
        {
            if ($route = $request->route()) {
                return $this->router->gatherRouteMiddleware($route);
            }
     
            return [];
        }
     
        /**
    Arguments
    1. Request {
        #json: null
        #convertedFiles: null
        #userResolver: Closure {
          class: "Illuminate\Auth\AuthServiceProvider"
          this: AuthServiceProvider { …}
          parameters: {
            $guard: {
              default: null
            }
          }
          use: {
            $app: Application { …}
          }
        }
        #routeResolver: Closure {
          class: "Illuminate\Routing\Router"
          this: Router { …}
          use: {
            $route: Route { …}
          }
        }
        +attributes: ParameterBag {}
        +request: ParameterBag {#1}
        +query: ParameterBag {#1}
        +server: ServerBag {}
        +files: FileBag {}
        +cookies: ParameterBag {}
        +headers: HeaderBag {}
        #content: null
        #languages: null
        #charsets: null
        #encodings: null
        #acceptableContentTypes: array:4 [
          0 => "text/html"
          1 => "application/xhtml+xml"
          2 => "application/xml"
          3 => "*/*"
        ]
        #pathInfo: "/catalog/products/nio"
        #requestUri: "/catalog/products/nio"
        #baseUrl: ""
        #basePath: null
        #method: "GET"
        #format: null
        #session: Store {}
        #locale: null
        #defaultLocale: "en"
        -isHostValid: true
        -isForwardedValid: true
        basePath: ""
        format: "html"
      }
      
    2. Response {}
      
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    Foundation
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    /
    Kernel.php
         */
        protected function dispatchToRouter()
        {
            return function ($request) {
                $this->app->instance('request', $request);
     
                return $this->router->dispatch($request);
            };
        }
     
        /**
         * Call the terminate method on any terminable middleware.
         *
         * @param  \Illuminate\Http\Request  $request
         * @param  \Illuminate\Http\Response  $response
         * @return void
         */
        public function terminate($request, $response)
        {
            $this->terminateMiddleware($request, $response);
     
            $this->app->terminate();
        }
     
        /**
         * Call the terminate method on any terminable middleware.
         *
         * @param  \Illuminate\Http\Request  $request
         * @param  \Illuminate\Http\Response  $response
         * @return void
         */
        protected function terminateMiddleware($request, $response)
        {
            $middlewares = $this->app->shouldSkipMiddleware() ? [] : array_merge(
                $this->gatherRouteMiddleware($request),
                $this->middleware
            );
     
            foreach ($middlewares as $middleware) {
                if (! is_string($middleware)) {
    Arguments
    1. Request {
        #json: null
        #convertedFiles: null
        #userResolver: Closure {
          class: "Illuminate\Auth\AuthServiceProvider"
          this: AuthServiceProvider { …}
          parameters: {
            $guard: {
              default: null
            }
          }
          use: {
            $app: Application { …}
          }
        }
        #routeResolver: Closure {
          class: "Illuminate\Routing\Router"
          this: Router { …}
          use: {
            $route: Route { …}
          }
        }
        +attributes: ParameterBag {}
        +request: ParameterBag {#1}
        +query: ParameterBag {#1}
        +server: ServerBag {}
        +files: FileBag {}
        +cookies: ParameterBag {}
        +headers: HeaderBag {}
        #content: null
        #languages: null
        #charsets: null
        #encodings: null
        #acceptableContentTypes: array:4 [
          0 => "text/html"
          1 => "application/xhtml+xml"
          2 => "application/xml"
          3 => "*/*"
        ]
        #pathInfo: "/catalog/products/nio"
        #requestUri: "/catalog/products/nio"
        #baseUrl: ""
        #basePath: null
        #method: "GET"
        #format: null
        #session: Store {}
        #locale: null
        #defaultLocale: "en"
        -isHostValid: true
        -isForwardedValid: true
        basePath: ""
        format: "html"
      }
      
    2. Response {}
      
    /
    var
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    /
    belkarolin
    /
    data
    /
    www
    /
    belkarolin.com
    /
    public
    /
    index.php
    |--------------------------------------------------------------------------
    | Run The Application
    |--------------------------------------------------------------------------
    |
    | Once we have the application, we can handle the incoming request
    | through the kernel, and send the associated response back to
    | the client's browser allowing them to enjoy the creative
    | and wonderful application we have prepared for them.
    |
    */
    
    $kernel = $app->make(Illuminate\Contracts\Http\Kernel::class);
    
    $response = $kernel->handle(
        $request = Illuminate\Http\Request::capture()
    );
    
    $response->send();
    
    $kernel->terminate($request, $response);
     
    Arguments
    1. Request {
        #json: null
        #convertedFiles: null
        #userResolver: Closure {
          class: "Illuminate\Auth\AuthServiceProvider"
          this: AuthServiceProvider { …}
          parameters: {
            $guard: {
              default: null
            }
          }
          use: {
            $app: Application { …}
          }
        }
        #routeResolver: Closure {
          class: "Illuminate\Routing\Router"
          this: Router { …}
          use: {
            $route: Route { …}
          }
        }
        +attributes: ParameterBag {}
        +request: ParameterBag {#1}
        +query: ParameterBag {#1}
        +server: ServerBag {}
        +files: FileBag {}
        +cookies: ParameterBag {}
        +headers: HeaderBag {}
        #content: null
        #languages: null
        #charsets: null
        #encodings: null
        #acceptableContentTypes: array:4 [
          0 => "text/html"
          1 => "application/xhtml+xml"
          2 => "application/xml"
          3 => "*/*"
        ]
        #pathInfo: "/catalog/products/nio"
        #requestUri: "/catalog/products/nio"
        #baseUrl: ""
        #basePath: null
        #method: "GET"
        #format: null
        #session: Store {}
        #locale: null
        #defaultLocale: "en"
        -isHostValid: true
        -isForwardedValid: true
        basePath: ""
        format: "html"
      }
      
    2. Response {}
      

    Environment & details:

    empty
    empty
    empty
    empty
    empty
    Key Value
    REDIRECT_REDIRECT_REDIRECT_UNIQUE_ID
    "XQrHLB4YjXBybGS@lV@3pwAAAAc"
    
    REDIRECT_REDIRECT_REDIRECT_STATUS
    "200"
    
    REDIRECT_REDIRECT_UNIQUE_ID
    "XQrHLB4YjXBybGS@lV@3pwAAAAc"
    
    REDIRECT_REDIRECT_STATUS
    "200"
    
    REDIRECT_UNIQUE_ID
    "XQrHLB4YjXBybGS@lV@3pwAAAAc"
    
    REDIRECT_HANDLER
    "application/x-httpd-php5"
    
    REDIRECT_STATUS
    "200"
    
    UNIQUE_ID
    "XQrHLB4YjXBybGS@lV@3pwAAAAc"
    
    HTTP_HOST
    "belkarolin.com"
    
    HTTP_X_FORWARDED_PROTO
    "http"
    
    HTTP_X_FORWARDED_PORT
    "80"
    
    HTTP_CONNECTION
    "close"
    
    HTTP_USER_AGENT
    "CCBot/2.0 (https://commoncrawl.org/faq/)"
    
    HTTP_ACCEPT
    "text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8"
    
    HTTP_ACCEPT_LANGUAGE
    "en-US,en;q=0.5"
    
    HTTP_IF_MODIFIED_SINCE
    "Sat, 20 Apr 2019 04:42:39 EDT"
    
    HTTP_ACCEPT_ENCODING
    "gzip"
    
    PATH
    "/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin"
    
    SERVER_SIGNATURE
    ""
    
    SERVER_SOFTWARE
    "Apache/2.4.6 (CentOS) mpm-itk/2.4.7-04 OpenSSL/1.0.2k-fips PHP/5.4.16"
    
    SERVER_NAME
    "belkarolin.com"
    
    SERVER_ADDR
    "127.0.0.1"
    
    SERVER_PORT
    "80"
    
    REMOTE_ADDR
    "34.235.143.190"
    
    DOCUMENT_ROOT
    "/var/www/belkarolin/data/www/belkarolin.com"
    
    REQUEST_SCHEME
    "http"
    
    CONTEXT_PREFIX
    "/php-bin/"
    
    CONTEXT_DOCUMENT_ROOT
    "/var/www/php-bin-isp-php70/belkarolin/"
    
    SERVER_ADMIN
    "webmaster@belkarolin.com"
    
    SCRIPT_FILENAME
    "/var/www/belkarolin/data/www/belkarolin.com/public/index.php"
    
    REMOTE_PORT
    "33475"
    
    REDIRECT_URL
    "/public/index.php"
    
    GATEWAY_INTERFACE
    "CGI/1.1"
    
    SERVER_PROTOCOL
    "HTTP/1.0"
    
    REQUEST_METHOD
    "GET"
    
    QUERY_STRING
    ""
    
    REQUEST_URI
    "/catalog/products/nio"
    
    SCRIPT_NAME
    "/public/index.php"
    
    ORIG_SCRIPT_FILENAME
    "/var/www/php-bin-isp-php70/belkarolin/php"
    
    ORIG_PATH_INFO
    "/public/index.php"
    
    ORIG_PATH_TRANSLATED
    "/var/www/belkarolin/data/www/belkarolin.com/public/index.php"
    
    ORIG_SCRIPT_NAME
    "/php-bin/php"
    
    PHP_SELF
    "/public/index.php"
    
    REQUEST_TIME_FLOAT
    1560987436.8242
    
    REQUEST_TIME
    1560987436
    
    APP_NAME
    "Laravel"
    
    APP_ENV
    "local"
    
    APP_KEY
    "base64:uxa8r7bu4bC4Wugtknnxtf19ioZbTW8/b3NNBmFdQp4="
    
    APP_DEBUG
    "true"
    
    APP_LOG_LEVEL
    "debug"
    
    APP_URL
    "http://localhost"
    
    DB_CONNECTION
    "mysql"
    
    DB_HOST
    "localhost"
    
    DB_PORT
    "3306"
    
    DB_DATABASE
    "lara"
    
    DB_USERNAME
    "lara"
    
    DB_PASSWORD
    "Q3x0K4z5"
    
    BROADCAST_DRIVER
    "log"
    
    CACHE_DRIVER
    "file"
    
    SESSION_DRIVER
    "file"
    
    SESSION_LIFETIME
    "120"
    
    QUEUE_DRIVER
    "sync"
    
    REDIS_HOST
    "127.0.0.1"
    
    REDIS_PASSWORD
    "null"
    
    REDIS_PORT
    "6379"
    
    MAIL_DRIVER
    "smtp"
    
    MAIL_HOST
    "smtp.mailtrap.io"
    
    MAIL_PORT
    "2525"
    
    MAIL_USERNAME
    "null"
    
    MAIL_PASSWORD
    "null"
    
    MAIL_ENCRYPTION
    "null"
    
    PUSHER_APP_ID
    ""
    
    PUSHER_APP_KEY
    ""
    
    PUSHER_APP_SECRET
    ""
    
    PUSHER_APP_CLUSTER
    "mt1"
    
    MAIL_SERVICE_RECIPIENT
    "inf@belkarolin.com"
    
    Key Value
    APP_NAME
    "Laravel"
    
    APP_ENV
    "local"
    
    APP_KEY
    "base64:uxa8r7bu4bC4Wugtknnxtf19ioZbTW8/b3NNBmFdQp4="
    
    APP_DEBUG
    "true"
    
    APP_LOG_LEVEL
    "debug"
    
    APP_URL
    "http://localhost"
    
    DB_CONNECTION
    "mysql"
    
    DB_HOST
    "localhost"
    
    DB_PORT
    "3306"
    
    DB_DATABASE
    "lara"
    
    DB_USERNAME
    "lara"
    
    DB_PASSWORD
    "Q3x0K4z5"
    
    BROADCAST_DRIVER
    "log"
    
    CACHE_DRIVER
    "file"
    
    SESSION_DRIVER
    "file"
    
    SESSION_LIFETIME
    "120"
    
    QUEUE_DRIVER
    "sync"
    
    REDIS_HOST
    "127.0.0.1"
    
    REDIS_PASSWORD
    "null"
    
    REDIS_PORT
    "6379"
    
    MAIL_DRIVER
    "smtp"
    
    MAIL_HOST
    "smtp.mailtrap.io"
    
    MAIL_PORT
    "2525"
    
    MAIL_USERNAME
    "null"
    
    MAIL_PASSWORD
    "null"
    
    MAIL_ENCRYPTION
    "null"
    
    PUSHER_APP_ID
    ""
    
    PUSHER_APP_KEY
    ""
    
    PUSHER_APP_SECRET
    ""
    
    PUSHER_APP_CLUSTER
    "mt1"
    
    MAIL_SERVICE_RECIPIENT
    "inf@belkarolin.com"
    
    0. Whoops\Handler\PrettyPageHandler